The purpose of this study was to determine the actual treatment adherence of new TB patients in China and to identify factors leading to patient medication non-adherence. The study was a prospective cohort analysis of 481 newly confirmed TB patients. The study found that traditional adherence monitoring/interventions (DOT) are less frequently practiced in high burden regions. Self-administration or family DOT is increasingly standard of care. 13.9% of patients had dosing observed by anyone, only 2.4% by health worker. Additionally, baseline adherence (both dosing implementation and persistence) for self-administering patients was found to be sub-optimal. One-third of participants experienced non-adherence, and patients’ lost to follow-up was not uncommon(– 28%). In conclusion, poor treatment supervision and heavy financial burden might be primary causes for non-adherence. More needs to be done to enhance treatment supervision practices and financial supports for both health providers and patients.
Tags: Huang, Infectious Diseases of Poverty, Lei, Liu, Sheng-Lan, Yong-Feng
Full Citation: Lei, Xun, et al. "Are Tuberculosis Patients Adherent to Prescribed Treatments in China? Results of a Prospective Cohort Study." Infectious Diseases of Poverty 5.1 (2016): 38.